At a glance
Which G93 code do I assign?
Encephalopathy splits on the cause the provider names rather than on severity or acuity. The Alphabetic Index sends the toxic, alcoholic, hypertensive and hepatic forms to codes outside subcategory G93.4, leaving G93.4 to hold the metabolic form, the unspecified form and a short list of named leukoencephalopathies.
Tabular notes
Operational & financial impact
Why specificity matters beyond the chart: risk adjustment, DRG assignment and denial exposure all follow from which code is selected.
Documentation checklist to support G93.41
Chart elements that support code selection and reduce specificity-driven denials.
FAQ
Yes. Code G93.41 is a valid five character billable code. Its parent G93.4, other and unspecified encephalopathy, is a subcategory header and cannot be reported on a claim. Category G93 cannot be reported either. Code G93.41 takes no seventh character.
The three sit at different points on one axis. Code R41.82, altered mental status, unspecified, is a symptom code. It carries an Excludes1 note reading altered mental status due to known condition, code to condition. It is displaced as soon as the record names a cause. Code F05, delirium due to known physiological condition, sits in Chapter 5 and carries a Code first instruction for the underlying physiological condition. Its inclusion terms include acute or subacute confusional state, delirium of mixed etiology, delirium superimposed on dementia and sundowning. Code G93.41 sits in Chapter 6 and carries no Code first instruction. No Excludes note stands between category F05 and subcategory G93.4. Both may be reported where the record documents both.
No. Code G93.41 does not appear in the CMS-HCC v28 ICD-10-CM mapping for payment year 2026. Codes G93.40 and G93.49 do not appear either. Hepatic encephalopathy (K76.82) does map, to HCC 63, Chronic Liver Failure/End-Stage Liver Disorders. Severity designation under the MS-DRG system and mapping under the risk adjustment model are separate questions and have to be checked separately.
The chart needs five things. The first is a provider statement of encephalopathy rather than a statement of confusion or altered mental status. The second is the metabolic derangement the provider attributes it to. The third is the patient's baseline mental status and a documented departure from it. The fourth is the same diagnosis and the same type carried consistently through the record. The fifth is treatment and monitoring directed at the condition. The Livanta Claims Review Advisor of October 2022 lists an examination showing altered mental status that is not the patient's baseline, consistent documentation that encephalopathy is present, consistent documentation of its type, and clinical support for that type as the elements reviewers check. The same publication names a record that says the patient was alert and oriented, and a diagnosis introduced only by a post discharge query, as reasons higher weighted DRG claims are changed.
Code G92.8. Toxic metabolic encephalopathy is an inclusion term at G92.8, other toxic encephalopathy. The single documented phrase resolves to one code and G93.41 is not added for it. Where the record instead documents a toxic encephalopathy from one cause and a metabolic encephalopathy from a separate cause, both codes are reported. Subcategory G93.4 carries an Excludes2 note for toxic (metabolic) encephalopathy (G92.8), which permits that pairing. AHA Coding Clinic, Second Quarter 2024, pages 14 and 15, addresses metabolic encephalopathy reported with toxic metabolic encephalopathy. Note that the code is G92.8 rather than G92. Category G92 itself is no longer billable.
The tabular does not fix the order. Subcategory G93.4 carries no Code first instruction, and no etiology and manifestation convention applies. Section II of the FY2027 ICD-10-CM Official Guidelines, effective 1 October 2026, defines the principal diagnosis as the condition established after study to be chiefly responsible for occasioning the admission. Where the encephalopathy is what brought the patient in and drove the workup, G93.41 can be sequenced first even where the note says it is due to a urinary tract infection. AHA Coding Clinic, Second Quarter 2018, page 22, addresses that sequencing and puts it on the condition found after study to be responsible for the admission. Two situations override this. Where severe sepsis is documented, the underlying infection is sequenced first, then a code from subcategory R65.2, then G93.41 as the acute organ dysfunction. Where the encephalopathy is integral to another documented condition, such as a postictal state, it is not reported separately at all.
The code is the same and the payment rules are not. MS-DRG assignment applies to inpatient claims only. On an outpatient or professional claim G93.41 supports medical necessity and the complexity of medical decision making rather than a DRG. Under Section IV.H of the FY2027 ICD-10-CM Official Guidelines, a diagnosis documented as probable, suspected, questionable or rule out is not coded as confirmed in the outpatient setting. On the inpatient side an uncertain diagnosis documented at discharge may be coded as confirmed under the UHDDS rules. Resolution during the stay does not remove the code. A secondary diagnosis is reportable when it required clinical evaluation, therapeutic treatment, diagnostic procedures, an extended length of stay or increased nursing care. Record the date the mental status returned to baseline rather than leaving a reviewer to infer it.
G93.41 is unchanged in the FY2027 update, effective 1 October 2026. The FY2027 tabular addenda add the inclusion term midline shift of brain at G93.5 and change nothing in subcategory G93.4. The FY2026 change sat in the MS-DRG grouper. CMS deleted MS-DRGs 077, 078 and 079, moved hypertensive encephalopathy (I67.4) into MS-DRGs 070, 071 and 072, and retitled that triplet from Nonspecific Cerebrovascular Disorders to Other Cerebrovascular Disorders. Those are the MS-DRGs a G93.41 principal diagnosis groups to under the FY2027 MS-DRG v44 grouper.
Related codes
Codes in the same family as G93.41. Only codes with a published page render as links.
Sibling codes in the G93 family
- G93.0: Cerebral cysts.
- G93.1: Anoxic brain damage, not elsewhere classified.
- G93.2: Benign intracranial hypertension.
- G93.31: Postviral fatigue syndrome.
- G93.32: Myalgic encephalomyelitis/chronic fatigue syndrome.
- G93.39: Other post infection and related fatigue syndromes.
- G93.40: Encephalopathy, unspecified.
- G93.42: Megalencephalic leukoencephalopathy with subcortical cysts.
- G93.43: Leukoencephalopathy with calcifications and cysts.
- G93.44: Adult-onset leukodystrophy with axonal spheroids.
- G93.45: Developmental and epileptic encephalopathy.
- G93.49: Other encephalopathy.
- G93.5: Compression of brain.
- G93.6: Cerebral edema.
- G93.7: Reye's syndrome.
- G93.81: Temporal sclerosis.
- G93.82: Brain death.
- G93.89: Other specified disorders of brain.
- G93.9: Disorder of brain, unspecified.
Additional codes to consider
Codes outside the G93 family considered alongside G93.41.
Companion: code alongside when documented
- R65.20: Severe sepsis without septic shock. Subcategory R65.2 names encephalopathy (metabolic) (septic) (G93.41) in its Use additional code list.
- R65.21: Severe sepsis with septic shock, under the same R65.2 note.
- R65.11: Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction, which names G93.41 in its own Use additional code list.
- M31.11: Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA], which names G93.41 in its Use additional code list.
- A41.9: Sepsis, unspecified organism, sequenced before the R65.2 code under its Code first note when severe sepsis is documented.
- E87.1: Hypo-osmolality and hyponatremia, permitted alongside G93.41 by the chapter 6 Excludes2 note for E00–E88.
- E87.0: Hyperosmolality and hypernatremia, under the same chapter 6 Excludes2 note.
- E87.20: Acidosis, unspecified, under the same chapter 6 Excludes2 note.
- R40.20: Unspecified coma, permitted alongside G93.41 by the chapter 6 Excludes2 note for R00–R94.
- G92.8: Other toxic encephalopathy, where a separate toxic cause is documented alongside the metabolic one, under the Excludes2 note at G93.4.
Consider instead
- G93.40: Encephalopathy, unspecified, where the provider names no cause.
- G93.49: Other encephalopathy, where a named form has no code of its own.
- G92.8: Other toxic encephalopathy, which carries toxic metabolic encephalopathy as an inclusion term.
- G92.9: Unspecified toxic encephalopathy.
- G92.0-: Immune effector cell-associated neurotoxicity syndrome, for ICANS following immune effector cellular therapy.
- K76.82: Hepatic encephalopathy.
- K72.01: Acute and subacute hepatic failure with coma.
- K72.91: Hepatic failure, unspecified with coma.
- I67.4: Hypertensive encephalopathy.
- G31.2: Degeneration of nervous system due to alcohol, which carries alcoholic encephalopathy as an inclusion term.
- G94: Other disorders of brain in diseases classified elsewhere, which carries a Code first instruction for the underlying disease.
- F05: Delirium due to known physiological condition.
- F10.231: Alcohol dependence with withdrawal delirium.
- R41.82: Altered mental status, unspecified.
- R41.0: Disorientation, unspecified, which carries delirium NOS as an inclusion term.
- E51.2: Wernicke's encephalopathy.
- E16.2: Hypoglycemia, unspecified, which the Alphabetic Index assigns to hypoglycemic encephalopathy.
- G93.1: Anoxic brain damage, not elsewhere classified, which the Alphabetic Index reaches from Encephalopathy, hypoxic through Damage, brain, anoxic.
- P91.60: Hypoxic ischemic encephalopathy [HIE], unspecified, for the newborn.
- G93.45: Developmental and epileptic encephalopathy.
Sources
All claims on this page derive from government and professional-standards sources.
- National Center for Health Statistics. (2026). International classification of diseases, tenth revision, clinical modification (ICD-10-CM) FY2027 files. https://www.cdc.gov/nchs/icd/icd-10-cm/files.html
- Centers for Medicare & Medicaid Services and National Center for Health Statistics. (2026). ICD-10-CM official guidelines for coding and reporting FY2027. https://ftp.cdc.gov/pub/Health_Statistics/NCHS/Publications/ICD10CM/2027/ICD-10-CM-October-1-2026-FY27-Guidelines.pdf
- Centers for Medicare & Medicaid Services. (2025). 2026 model software/ICD-10 mappings. https://www.cms.gov/medicare/payment/medicare-advantage-rates-statistics/risk-adjustment/2026-model-software-icd-10-mappings
- Centers for Medicare & Medicaid Services. (2026). MS-DRG classifications and software, version 44. https://www.cms.gov/medicare/payment/prospective-payment-systems/acute-inpatient-pps/ms-drg-classifications-and-software
